Wei Wang,a Research Assistant Professor at Shenzhen University of Advanced Technology (SUAT), received his Ph.D. in Regenerative Medicine from the Institute of Zoology, Chinese Academy of Sciences. He obtained his B.Sc. in Life Sciences from Sichuan University. He conducted postdoctoral research at Zhongshan School of Medicine, Sun Yat-sen University, and Shenzhen Bay Laboratory, and later served as an Assistant Researcher at Shenzhen Bay Laboratory. His research focuses on stem cells and epigenetic regulation, as well as epigenetic mechanisms underlying autism spectrum disorder. Dr. Wang has led one General Program project funded by the Guangdong Basic and Applied Basic Research Foundation. In recent years, he has published three papers as first author/co-first author in leading international journals, including Science Translational Medicine, Nature Communications, and Genome Medicine, with his study on KAT7-mediated regulation of aging highlighted by Faculty Opinions. He has also contributed to four additional SCI-indexed publications.

1.Stem Cells and Epigenetic Regulation

2.Epigenetic Regulation in Autism Spectrum Disorder

Education:

2014-09–2021-01: Institute of Zoology, Chinese Academy of Sciences ,Doctor of philosophy in Regenerative Medicine (Supervisor: Prof. Guanghui Liu)

2010-09–2014-06: College of Life Sciences, Sichuan University Bachelor of Science

Work Experience:

2026-6–Present: Shenzhen University of Advanced Technology,Research Assistant Professor (Prof. Zhonghua Gao's group)

2023-09-2025-12: Shenzhen Bay Laboratory Assistant Researcher (Prof. Chen Yu's group)

2021-09-2023-09: Zhongshan School of Medicine, Sun Yat-sen University/Shenzhen Bay Laboratory , Postdoctoral (Prof. Chen Yu and Tao Xu's group)

Research Projects:

1. Guangdong Basic and Applied Basic Research Foundation, 2024–2026, ongoing, Principal Investigator

2. General Program, National Natural Science Foundation of China (NSFC), (2026–2029, ongoing), Participant

Selected publications:

1.(First author, IF19.2) Wang W#, Zheng Y#, Sun S#, Li W#, Song M, Ji Q, Wu Z, Liu Z, Fan Y, Liu F, Li J, Esteban CR, Wang S, Zhou Q, Belmonte JCI, Zhang W, Qu J, Tang F, Liu GH. A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence. Sci. Transl. Med. 13, eabd2655 (2021). (Faculty Opinions Highlight).

2.(Co-first author, IF18.1) Xudong Zou#, Wei Wang#, Yinuo Wang#, Hui Chen#, Xing Li, Shuxin Chen, Feihong Weng, Qin Li, Chen Yu, Lei Li. Alternative tandem transcription initiation links noncoding variants to human disease through translational control. Nature Communications. https://doi.org/10.1038/s41467-026-76741-8 (2026)

3.(Co-first author, IF10.8) Kewei Xiong#, Wei Wang#, Ruofan Ding, Dinglin Luo, Yangmei Qin, Xudong Zou, Jiguang Wang, Chen Yu, Lei Li. Multimodal integration of single cell ATAC-seq data enables highly accurate delineation of clinically relevant tumor cell subpopulations. Genome Medicine.10.1186/s13073-026-01599-w (2026).

4.Jing, Yaobin#；Jiang, Xiaoyu#；Ji, Qianzhao；Wu, Zeming；Wang Wei；Liu, Zunpeng； Guillen-Garcia, Pedro；Esteban, Concepcion Rodriguez；Reddy, Pradeep；Horvath, Steve； Li, Jingyi；Geng, Lingling；Hu, Qinchao；Wang, Si；Belmonte, Juan Carlos Izpisua；Ren, Jie； Zhang, Weiqi；Qu, Jing；Lui, Guang-Hui.Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation. Cell. Stem. Cell. 10.1016/j.stem.2023.09.007 (2023).

5.Ma S#, Sun S#, Geng L#, Song M#, Wang W, Ye Y, Ji Q, Zou Z, Wang S, He X, Li W, Esteban CR, Long X, Guo G, Chan P, Zhou Q, Belmonte JCI, Zhang W, Qu J, Liu GH. Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging. Cell. 180(5):984-1001 (2020).

6.Geng L#, Liu Z#, Zhang W#, Li W, Wu Z, Wang W, Ren R, Su Y, Wang P, Ju Z, Chan P, Song M, Qu J, Liu GH. Chemical Screen Identifies a Geroprotective Role of Quercetin in Premature Aging. Protein Cell. 10(6): 417-435 (2019).

7.Wu Z#, Zhang W#, Song M#, Wang W, Wei G, Li W, Lei J, Huang Y, Sang Y, Chan P, Chen C, Qu J, Suzuki K, Belmonte JCI, Liu GH. Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome. Protein Cell. 9: 333-350 (2018).