Binyu Lu, Research Assistant Professor at Shenzhen Institute of Technology, Ph.D. in Chemistry, recognized as a High-level Talent of Shenzhen (Pengcheng Peacock Program, Category C).

Dr. Lu received her bachelor's degree in chemistry from Nankai University and obtained both her master's and doctoral degrees in chemistry from Case Western Reserve University (CWRU), USA. After completing her Ph.D., she continued postdoctoral research at CWRU. Her current research focuses on elucidating the physiological functions of ferritin in mammalians.

Iron metabolism and exploration of ferritin function using mouse models

Education

2013.09-2019.01: Case Western Reserve University, Ph.D. in Chemistry (Advisor: Thomas Kelley)

2011.09-2013.05: Case Western Reserve University, M.S. in Chemistry

2007.09-2011.06: Nankai University, B.S. in Chemistry

Professional Experience

2025.07–present: Research Assistant Professor, Shenzhen University of Technology (Bing Zhou’s group)

2023.08–2025.06: Assistant Researcher, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences

2021.08–2023.08: Postdoctoral Fellow, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences

2019.05–2021.05: Postdoctoral Fellow, Case Western Reserve University

APSselect Award (Jun 2020)

Research Projects

1. National Natural Science Foundation of China (General Program), 01/2024–12/2027, ongoing, participant.

Selected publications

1. Lu B, Guo S, Zhao J, Wang X, Zhou B. Adipose knockout of H-ferritin improves energy metabolism in mice. Mol Metab. 2024;80:101871. doi:10.1016/j.molmet.2024.101871

2. Boyne K, Corey DA, Zhao P, Lu B, …& Kelley TJ. Carbonic anhydrase and soluble adenylate cyclase regulation of cystic fibrosis cellular phenotypes. Am J Physiol-Lung Cell Mol Physiol. 2022;322(3):L333-L347. doi:10.1152/ajplung.00022.2021

3. Lu B, Corey DA, Kelley TJ. Resveratrol restores intracellular transport in cystic fibrosis epithelial cells. Am J Physiol - Lung Cell Mol Physiol. 2020;318(6):L1145-L1157. doi:10.1152/ajplung.00006.2020

4. Rymut SM, Lu B, Perez A, et al. Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells. Am J Physiol-Lung Cell Mol Physiol. 2019;316(6):L1081-L1093. doi:10.1152/ajplung.00369.2018

5. Lu B, Li L, Schneider M, et al. Electrochemical measurement of membrane cholesterol correlates with CFTR function and is HDAC6-dependent. J Cyst Fibros. 2019;18(2):175-181. doi:10.1016/j.jcf.2018.06.005

6. Li L, Lu B, Jiang D,Shin M,Kelley T,Burgess JD. Cell Plasma Membrane Cholesterol as a Diagnostic. Curr Opin Electrochem. 2017;2(1):82-87. doi:10.1016/j.coelec.2017.04.004

Conference Presentations:

1.2022.11: Corey D, Lu B, Kelley T. North American Cystic Fibrosis Conference (NACFC), Poster Presentation, Philadelphia, US.

Title: "Carbonic anhydrase12 knockout mimics cystic fibrosis cellular phenotypes".

2.2019.10: Lu B, Corey D, Hodges CA, Cotton C, Kelley T. North American Cystic Fibrosis Conference (NACFC), Poster Presentation, Nashville, US.

Title: "Electrochemical membrane cholesterol measurement as a biomarker for pharmacological F508del CFTR correction".