Fuyu Duan, Research Assistant Professor at Shenzhen University of Advanced Technology (SUAT), holds a Ph.D. in Biology from Tsinghua University School of Medicine and subsequently worked as a postdoctoral fellow and assistant researcher at Guangzhou Women and Children's Medical Center. His research specializes in the directed differentiation and therapeutic applications of human pluripotent stem cells (hPSCs). Dr. Duan secured funding as Principal Investigator for one China Postdoctoral Science Foundation project and served as a core member of a major national stem cell research initiative. He contributed to establishing one industry-recognized technical specification (group standard) and has published 6 first/co-first-author papers in journals including Stem Cell Research & Therapy, Nature, Nature Communications, and, alongside 10+ co-authored publications. He also holds four authorized Chinese invention patents, demonstrating his innovative contributions to stem cell technology.

Education

2012.09–2019.01: Tsinghua University, Ph.D. in Biology (Advisor: Associate Professor Jie Na)

2008.09–2012.06: Minzu University of China, B.S. in Biology

Professional Experience

2024.11–Present: Shenzhen University of Technology (SUAT), Research Assistant Professor (Team: Qizhou Lian)

2020.11–2024.05: Guangzhou Women and Children's Medical Center (Joint Training with Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences), Postdoctoral Researcher

2019.03–2020.11: Tsinghua University, Research Assistant

Honorary and awards

• Faculty Outstanding Research Output Award (2023)

• Tsinghua University Graduate Comprehensive Excellence Second Prize (2018)

• Best Poster Award, 6th Chinese Stem Cell Annual Conference (2016)

• Beijing Outstanding Graduate Award (2012)

•National Scholarship (2011)

Research Projects

1. 70^thChina Postdoctoral Science Foundation General Funding (2021–2023, Completed), Principal Investigator

2. 2022 National Key R&D Program of the Ministry of Science and Technology (2023.01–Present, Ongoing), Core Team Member

3. Collaborative Project, Shenzhen University of Technology Education Foundation (2025.03–Present, Ongoing), Subproject Leader

4. General Program, National Natural Science Foundation of China (NSFC) (2020.01–2023.12, Completed), Participant

5. Major Research Plan, National Natural Science Foundation of China (NSFC) (2018.01–2020.12, Completed), Participant

Selected publications

1.Fuyu Duan; Rujin Huang; Fengzhi Zhang; Yonglin Zhu; Lin Wang; Xia Chen; Lufeng Bai; Wei Guo; Sophia Chia-Ning Chang; Xiaoyu Hu; Jie Na*Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells,Stem Cell Research & Therapy, 2018, 9(1)

2.Qizhou Lian^#*; Kui Zhang^#; Zhao Zhang^#;Fuyu Duan^#; Liyan Guo^#; Weiren Luo; Bobo Wing-Yee Mok; Abhimanyu Thakur; Xiaoshan Ke; Pedram Motallebnejad; Vlad Nicolaescu; Jonathan Chen; Chui Yan Ma;Xiaoya Zhou; Shuo Han; Teng Han; Wei Zhang; Adrian Y. Tan; Tuo Zhang; Xing Wang; Dong Xu; Jenny Xiang; Aimin Xu; Can Liao; Fang-Ping Huang; Ya-Wen Chen; Jie Na; Glenn Randall; Hung-fat Tse; Zhiwei Chen; Yin Chen; Huanhuan Joyce Chen*;Differential effects of macrophage subtypes on SARSCoV-2 infection in a human pluripotent stem cell-derived model,Nature Communications, 2022 Apr 19;13(1):2028.

3.Yuling Han^#; Xiaohua Duan^#; Liuliu Yang^#; Benjamin E. Nilsson-Payant^#; Pengfei Wang^#;Fuyu Duan^#; Xuming Tang^#; Tomer M. Yaron^#; Tuo Zhang; Skyler Uhl; Yaron Bram; Chanel Richardson; Jiajun Zhu; Zeping Zhao; David Redmond; Sean Houghton; Duc-Huy T. Nguyen; Dong Xu; Xing Wang; Jose Jessurun; Alain Borczuk; Yaoxing Huang; Jared L. Johnson; Yuru Liu; Jenny Xiang; Hui Wang; Lewis C. Cantley; Benjamin R. tenOever; David D. Ho; Fong Cheng Pan; Todd Evans; Huanhuan Joyce Chen; Robert E. Schwartz; Shuibing Chen ;Identification of SARS-CoV-2 inhibitors using lung and colonic organoids,Nature, 2020, 589: 270-275

4.Yaxuan Zhang^#, Xingwu Zhang^#,Fuyu Duan^#; Huimin Qiao^#; Mingli Gong^#; Hui Qiu; Xia Chen; Peiliang Wang; Yuan He; Qiang Ding*; Jie Na*.Modeling antiviral response in the liver using human pluripotent stem cell-derived macrophages,Life Medicine, 2024, 3(1)

5.Yaxuan Zhang^#, Hui Qiu^#,Fuyu Duan^#,Haoran An^#, Huimin Qiao, Xingwu Zhang, Jing-Ren Zhang, Qiang Ding, and Jie Na*；A Comparative Study of Human Pluripotent Stem Cell-Derived Macrophages in Modeling Viral Infections.Viruses,2024, 16(4):552.

6.Zhao Zhang^#; Liyan Guo^#; Xiaoxia Lu^#; Che Zhang^#; Li Huang^#; Xianfeng Wang^#;Fuyu Duan^#; Huiying Liang; Peikai Chen; Liang Zeng; Jianbo Shao; Hui Li; Le Li; Li Liu; Cheng Li; Jinqiu Zhang; Chui Yan Ma; Ka Yi Kwan; Wei Liu; Yi Xu; Xiaoqiong Gu; Hua Jiang; Hui Du; Ting Zhang; Yanheng Wu; Guangyin Yu; Junhui Chen; Ruibang Luo; Can Liao; Hung-fat Tse; Zhiwei Chen; Huanhuan Joyce Chen; Huimin Xia; Qizhou Lian*; Clinical analysis and pluripotent stem cells-based model reveal possible impacts of ACE2 and lung progenitor cells on infants vulnerable to COVID-19,Theranostics, 2021, 11(5): 2170-2181

Granted Patents

1.Na Jie; Duan Fuyu.A Method for Differentiating Macrophages from Human Pluripotent Stem Cells.Granted: 2023-05-09, Patent No.: CN110607277B

2.Na Jie;Duan Fuyu; Zhu Yonglin.A Method for Differentiating Human Pluripotent Stem Cells into Hematopoietic Stem Cells and Culture Additive.Granted: 2021-08-06, Patent No.: CN108300695B

3.Na Jie; Zhu Yonglin; Zhang Fengzhi;Duan Fuyu.A Method for Preparing Vascular Endothelial Cells and Its Dedicated Kit.Granted: 2021-04-27, Patent No.: CN108048390B

4.Na Jie;Duan Fuyu;Li Jinyang.A Method for Enhancing Non-Integrated Gene Expression in Human Cells.Granted: 2016-09-21, Patent No.: CN103923920B

Conference Presentations:

1.2018.06:Fuyu Duan, Rujin Huang, et al.International Society for Stem Cell Research (ISSCR) Annual Meeting, Poster Presentation, Melbourne, Australia.

Title:"Highly Efficient Hematopoietic and Macrophage Differentiation from Human Pluripotent Stem Cells using a Simple Monolayer Culture System"

2.2016.09:Fuyu Duan, Fengzhi Zhang, et al.6th Chinese Society for Stem Cell Research (CSSCR) Annual Conference, Poster Presentation, Changchun, China.

Title:"Precise Control of Canonical Wnt Signaling Enables Highly Efficient Hematopoietic Differentiation from Human Pluripotent Stem Cells"

3.2015.11:Lin Wang, Fengzhi Zhang,Fuyu Duan, et al.5th Chinese Society for Stem Cell Research (CSSCR) Annual Conference, Poster Presentation, Chongqing, China.

Title:"MESP1 Promotes Human Cardiomyocyte Differentiation by Suppressing Canonical Wnt Signaling"

1. Development and application of pluripotent stem cell-derived immune cells

2. Engineered mesenchymal stromal cells and exosome-based delivery systems for rare neurological disorders