谢黎炜博士，深圳理工大学合成生物学院，长聘教研副教授。研究聚焦肠道菌群介导的组织间交互调节与人类健康，内容涉及肠道菌群与宿主营养代谢交互调节机理在代谢性疾病中的作用机制和转化应用。形成了“基础研究-技术转化-临床应用”的全链条创新体系。在基础研究层面，团队聚焦肠道菌群结构与功能解析、微生物组大数据分析技术开发，通过多组学方法揭示微生物与宿主互作机制；在临床研究方面，重点探索肠道菌群干预策略（如益生菌）对代谢性疾病（肥胖、糖尿病）和胃肠道疾病（如溃疡性结肠炎）的临床应用；在转化应用领域，推动基于微生物发酵技术和合成生物技术在生物制造和健康产品的开发和应用。团队通过整合生理学、生物信息学与临床医学，实现了从微生物和宿主以及从基础理论到临床实践的有效转化。

1. 肠道微生态与人类健康

2. 骨骼肌和脂肪干细胞生理与代谢调控

3. 微量元素代谢与人类健康

学习经历

2009.08-2013.05 美国佛罗里达大学，营养科学，博士

2007.08-2009.05 美国纽约州立大学布法罗分校，生物科学，学士

2003.09-2007.08 西安科技大学，自动化，学士

工作经历

2026.01-至今 深圳理工大学，长聘教研副教授

2017.05-2025.12 广东省科学院微生物研究所，华南应用微生物国家重点实验室，肠道微生态与健康团队，研究员、国重主任助理

2014.05-2017.04 美国乔治亚大学，分子医药中心，博士后研究员

2013.07-2014.04 美国密歇根大学，医学院，分子与整合生理系，博士后研究员

1.Q. An, R. Wei, Z. Huang, Y. Tang, M. Wang, S. He, K. Huang, Z. Liu, M. Zhang, R. Li, J. Huang, K. Zhang, J. Ji, L. Xie, Q. Ma. Palmitoylation of Tfr1 enhances platelet ferroptosis and liver injury in heat stroke. Acta Pharmaceutica Sinica B, 2025. https://doi.org/10.1016/j.apsb.2025.10.027

2.B. Liu, Y. Liu, S. Xu, Q. Wu, D. Wu, L. Zhan, Y. Liao, Y. Mai, M. Zheng, S. Wang, Y. Chen, Z. Huang, X. Luo, Z. Xie, X. Pan, G. Yu, L. Xie. EasyMultiProfiler: An Efficient Multi-Omics Data Integration and Analysis Workflow for Microbiome Research. Science China Life Sciences. 2025, In press. doi: 10.1007/s11427-025-3035-0.

3.X. Yao, X. Mai, Y Tian, Y. Liu, G. Jin, Z. Li, S. Chen, X. Dai, L. Huang, Z. Fan, G. Pan, X. Pan, X. Li, M. C. Yu, J Sun, J. Ou, H. Chen, L. Xie. Skeletal Muscle-specific Bambi deletion induces hypertrophy and oxidative switching coupling with adipocyte thermogenesis against metabolic disorders. Science China Life Sciences. 2025 Jan 13. doi: 10.1007/s11427-023-2586-x

4.K. Ding, Z. Zhang, Z. Han, L. Shi, X. Li, Y. Liu, Z. Li, C. Zhao, Y. Cui, L. Zhou, B. Xu, W. Zhou, Y. Zhao, Z. Wang, H. Huang, L. Xie, X. Chen, Z. Chen. Liver ALKBH5 regulates glucose and lipid homeostasis independently through GCGR and mTORC1 signaling. Science. 2025 Feb 28;387(6737):eadp4120. doi: 10.1126/science.adp4120

5.S. Chen, L. Huang, B. Liu, H. Duan, Z. Li, Y. Liu, H. Li, X. Fu, J. Lin, Y. Xu, L. Liu, D. Wan, Y. Yin, L. Xie. Dynamic Changes in Butyrate Levels Regulate Satellite Cell Homeostasis by Preventing Spontaneous Activation During Aging. Science China Life Sciences. 2024, 67, 745–764. doi: 10.1007/s11427-023-2400-3

6.S. Chen, P. Zhang, H. Duan, J. Wang, Y. Qiu, Z. Cui, Y. Yin, D. Wan, L. Xie. Gut microbiota in muscular atrophy development, progression and treatment: New therapeutic targets and opportunities. The Innovation, 2023 Jul 10;4(5):100479. doi: 10.1016/j.xinn.2023.100479

7.L. Huang, G. Pan, Y. Feng, Z. Fan, K. Ma, R. Wang, G. Wang, G. Huang, S. Huang, Y. Hou, M. Huang, L. Xie, Y. Ma. Microbial network signatures of early colonizers in infants with eczema. iMeta.2023 e90. doi: 10.1002/imt2.90

8.H. Ding, S. Chen, X. Pan, X. Dai, G. Pan, Z. Li, X. Mai, Y. Tian, S. Zhang, B. Liu, G. Cao, Z. Yao, X. Yao, L. Gao, L. Yang, X. Chen, J. Sun, H. Chen, M. Han, Y. Yin, G. Xu, H. Li, W. Wu, Z. Chen, J. Lin, L. Xiang, J. Hu, Y. Lu, X. Zhu, L. Xie. Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis. Journal of Cachexia, Sarcopenia and Muscle, 2021 Jun;12(3):746-768. doi: 10.1002/jcsm.12700

9.J. Li, X. Pan, G. Pan, Z. Song, Y. He, S. Zhang, X. Ye, X. Yang, E. Xie, X. Wang, X. Mai, X. Yin, B. Tang, X. Shu, P. Chen, X. Dai, Y. Tian, L. Yao, M. Han, G. Xu, H. Zhang, J. Sun, H. Chen, F. Wang, J. Min and L. Xie. Transferrin Receptor 1 Regulates Thermogenic Capacity and Cell Fate in Brown/Beige Adipocytes. Advanced Science, 2020 Apr 24;7(12):1903366. doi: 10.1002/advs.201903366

10.L. Xie, A. Yin, A.S. Nichenko, A.M. Beedle, J.A. Call, H. Yin, Transient HIF2 Inhibition Accelerates Muscle Regeneration by Promoting Satellite Cell Proliferation. J Clin Invest. 2018 Jun 1;128(6):2339-2355. doi: 10.1172/JCI96208